Breast cancer hormonal therapy treatment
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AIs work by blocking aromatase from making estrogen. Taking tamoxifen for 10 years is considered more effective than taking it for 5 years, but you and your doctor will decide the best schedule of treatment for you. Hormone therapy is a form of systemic therapy, meaning it reaches cancer cells almost anywhere in the body and not just in the breast. It stops estrogen from connecting to the cancer cells and telling them to grow and divide.
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Hormone Therapies For Breast Cancer Treatment
Aromatase inhibitors AIs are drugs that stop estrogen production. For most post-menopausal women whose cancers are hormone receptor-positive, most doctors recommend taking an AI at some point during adjuvant therapy. The benefits of taking these drugs outweigh the risks for almost all women with hormone receptor-positive breast cancer. Right now, standard treatment is to take these drugs for about 5 years, or to alternate with tamoxifen for a total of at least 5 years, or to take in sequence with tamoxifen for at least 3 years. The most common side effects of tamoxifen and toremifene are.. This may allow some other hormone therapies, such as AIs, to be used. Tamoxifen is an option for some women who cannot take an AI.
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Breast cancer and hormone therapy
If you are taking an AI, your bone density may be tested and you may also be given drugs, such as bisphosphonates or denosumab Xgeva, Prolia , to strengthen your bones. Hormone therapy is a form of systemic therapy, meaning it reaches cancer cells almost anywhere in the body and not just in the breast. Possible side effects. Some hormone treatments work by lowering estrogen levels. Because of this, it is called a selective estrogen receptor modulator SERM.
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